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Annual Report
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Details of LRI
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History of research subjects
History of research subjects
This is the list of research subjects under JCIA LRI program.

Blue-colored background shows the research period of each subject.
You can jump to the corresponding reports by a click of pdf icon on the list.
Annual reports will be issued in every June, and this list will be renewed accordingly.
NAME TITLE Annual
Report
2013
Annual
Report
2014
Annual
Report
2015
Annual
Report
2016
Annual
Report
2017
Annual
Report
2018
Annual
Report
2019
12_S01-01 Akihiro Tokai Probabilistic Exposure Evaluation Model for Relatively Small-scale
Occupational Workplace
pdf pdf pdf
12_S01-02 Hiroshi Yamazaki Human physiologically-based pharmacokinetic modeling of@industrial chemicals with chimeric mice with humanized liver pdf pdf pdf
12_S01-03 Kohji Aoyama Establishment of animal testing for the prediction of respiratory sensitizing potential of chemicals pdf pdf pdf
13_S01-01 Masaharu Seno Development of the Novel Method with iPSCs to Assess Chemical Compounds for the Risk of CSC Induction pdf pdf pdf pdf
16_S01-01 Bin-Le Lin Advanced system development for the hazard predicition and the environmental risk assessment/management of chemical substances
Subtitle: Development of the sophisticated basis tool for environmental hazard prediction
pdf pdf
16_S01-02 Toshihiko Kasahara Prediction method (Amino acid Derivative Reactivity Assay: ADRA) for skin sensitization using novel lysine and cysteine derivatives pdf pdf
12_S02-01 Yasuo Yoshioka Evaluation of the relationship between physicochemical properties
and biodistribution of nanomaterials
pdf pdf
13_S02-01 Hitoshi Iwahashi Study on the cellular and environmental effect related with solubility
of industrial nanomaterials
pdf pdf
13_S03-01 Kaeko Kamei Study on the mechanism of sick building syndrome and
development of risk assessment system utilizing Drosophila
pdf pdf pdf
15_S03-01 Takayuki Yoshimoto Establishment of in vitro evaluation system for the prediction of
respiratory sensitizing potential of chemicals
pdf pdf pdf pdf
12_S04-01 Tatsuya Takagi Development of in silico Prediction Model on Environmental Fate of Chemical Substances pdf pdf
12_PT01-01 Hiromi Wada Multi-functional testing method for attention ability by elaborating the target detection method and application to developmental neurotoxicology : testing for selective, sustained, shifted, and bisectional attention pdf
12_PT01-02 Bin-Le Lin Development of a user-friendly risk assessment tool for voluntary environmental risk
assessment and management by business operators
pdf pdf pdf
12_PT01-03 Takashi Morita Research for establishing new method for risk assessment of chemical toxicity using gene-modified ES cells pdf
12_PT01-04 Nobuhiro Tanuma Development of mice visualizing "Metabolic reprograming" at early phase of tumorigenesis, and its application to caricinogenicity tests pdf pdf
12_PT01-05 Takeshi BAMBA Development of metabolic profiling system for in vitro evaluation of
endocrine disruption by chemical substances
pdf pdf
12_PT01-06 Yoshimasa Takahashi Sophisticated hazard prediction by active QSAR modeling pdf pdf pdf
13_PT01-01 Yuhei Nishimura Development of in vivo fluorescent imaging of neuronal
differentiaon in zebrafish for developmental neuotoxicity testing
pdf pdf pdf pdf
13_PT01-02 Kohji Yamakage Applied research of a novel in vitro method for developmental
toxicity to facilitate the industrial utilization
pdf pdf
13_PT01-03 Kouichi Yoshinari Development of a combined in vitro/in silico system to predict and
evaluate the complex hepatotoxicity of chemical compounds.
pdf pdf pdf
15_PT01-01 Tsuyoshi Nakanishi Development of new in vivo screening method to validate the
low-dose effects induced by estrogenic chemicals using estrogen
reporter mice
pdf pdf pdf pdf
16_PT01-01 Shunichi Takeda Establishment of a comprehensive test for identifying mutagenic chemical compounds and molecular mechanisms underlying mutagenesis. pdf pdf
16_PT01-02 Yoshihiro Uesawa Construction of prediction models for toxicities induced by drugs and chemicals based on chemical structures and AOP pdf pdf pdf
17_PT01-01 FUKUDA@Junji Chip device for in vitro systemic toxicology pdf pdf
17_PT01-02 Miyazaki, Wataru Development of a new screening and predicting method using cfDNA to measure the effects of environmental chemicals in whole organs and its application for fetal exposure. pdf pdf
15_PT02-01 Yukari Totsuka Construction of the novel in vitro evaluation systems based on the
genotoxic mechanisms of nanomaterials
pdf pdf
17_PT02-01 Hiroyuki Tsuda Establishment of mechanism based assay protocol for hasard and carcinogenic risk of carbon based nanomaterisals. pdf pdf
12_PT03-01 Akira Nakamura Development of high sensitivity in vitro assessment system of chemical-mediated hypersensitivity by using serine protease inhibitor-deficient cells.
Subtitle: Analysis of in vitro assessment for respiratory allergy
pdf pdf pdf pdf pdf pdf
13_PT03-01 Hiroyuki Kusuhara Quantitative prediction of the pharmacokinetics of chemical substances by the use of
mathematical model with considering the age-dependent functional changes of metabolic
enzymes and transporters
pdf pdf pdf
12_PT04-01 Norihide Nakada Comprehensive evaluation methods for chemicals registered in PRTR. pdf pdf pdf
12_PT04-02 Yuhei INAMORI Development of Ecosystem Risk Impact Assessment System Methods for Chemicals using Microcosm Systems pdf pdf
16_PT04-01 Kei NAKAYAMA Development of the platform to manage the monitoring data of chemicals in environment, ChemTHEATRE pdf pdf pdf
13_PT05-01 Kazumasa Hirata Development and practical verification of novel comprehensive
monitoring system for multiple contaminations of environmental
pollutants in Mekong River basin
pdf pdf pdf pdf
17_S05-01 Hiroyuki Kusuhara Development of a novel approach for analyzing the biological actions of chemicals based on the deep phenotyping method. pdf pdf
18_R01-01 Masaaki Miyazawa Validation study on in vitro skin sensitization test method, EpiSensA, useing reconstructed human epidermis model pdf
18_R04-01 Kamo, Masashi Exploring roles and simple estimation methods of species sensitivity distribution for deriving PNECs pdf
18_R05-01 Tatarazako Norihisa Study on the contribution of microplastics to bioaccumulation and biological magnification towards fish pdf
19_R01-01 FUJIBUCHI WATARU Development of rapid, accurate, and low-cost AI drug hazard assessment method by human stem cell test
19_R03-01 Takayuki Yoshimoto Development of a novel alternative method for evaluation of sensitizing potential and allergenicity by measuring human T cell activation and differentiation (Key event 4)
19_R05-01 Yuji Oshima Construction of pharmacokinetic model to degradated microplastic-absorpted chemicals in fish and their risk analysis
19_D08-01 Shinichi KURODA Elucidation of Formation Mechanism of Microplastics
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